KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCTP2
All Species:
14.85
Human Site:
S738
Identified Species:
40.83
UniProt:
Q6DN12
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6DN12
NP_001153115.1
878
99596
S738
S
I
Q
D
S
Q
E
S
T
D
I
D
D
E
E
Chimpanzee
Pan troglodytes
XP_001138198
729
83930
D590
R
D
T
D
M
L
E
D
E
E
E
E
D
D
K
Rhesus Macaque
Macaca mulatta
XP_001099450
873
98991
D733
G
K
V
S
S
I
Q
D
S
Q
E
S
T
D
I
Dog
Lupus familis
XP_545835
879
100077
S739
S
I
Q
D
S
Q
E
S
T
D
I
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJH2
878
100159
S738
S
T
Q
D
S
Q
E
S
T
D
V
E
E
E
G
Rat
Rattus norvegicus
XP_218795
872
99514
S732
S
T
Q
D
S
Q
D
S
T
D
I
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508907
765
87913
S625
T
V
I
D
S
L
L
S
L
K
E
E
E
G
N
Chicken
Gallus gallus
XP_413880
513
58797
G374
D
K
E
S
E
K
K
G
I
I
D
R
I
H
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690994
754
85704
L615
N
I
G
R
V
R
N
L
F
R
A
V
S
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.6
95.7
92.7
N.A.
89.2
88.6
N.A.
40.7
43.1
N.A.
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.3
97.3
96
N.A.
94.5
93.8
N.A.
59
50.2
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
6.6
86.6
N.A.
66.6
73.3
N.A.
20
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
26.6
100
N.A.
86.6
93.3
N.A.
46.6
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
67
0
0
12
23
0
45
12
12
23
23
0
% D
% Glu:
0
0
12
0
12
0
45
0
12
12
34
56
45
45
34
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
0
0
0
12
0
0
0
0
0
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
34
12
0
0
12
0
0
12
12
34
0
12
0
12
% I
% Lys:
0
23
0
0
0
12
12
0
0
12
0
0
0
0
12
% K
% Leu:
0
0
0
0
0
23
12
12
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
45
0
0
45
12
0
0
12
0
0
0
0
0
% Q
% Arg:
12
0
0
12
0
12
0
0
0
12
0
12
0
0
0
% R
% Ser:
45
0
0
23
67
0
0
56
12
0
0
12
12
0
12
% S
% Thr:
12
23
12
0
0
0
0
0
45
0
0
0
12
0
0
% T
% Val:
0
12
12
0
12
0
0
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _